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CAT-240 CA Clarity PPM v12 traffic Analyst

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CA’s readability PPM v. 13: now not each traffic project is a Job for the Cloud | killexams.com actual questions with brain dumps

manner back in 1984, a corporation known as applied traffic technology Corp. produced a partly open supply venture management device referred to as Open Workbench. After it became a fraction of a company referred to as Niku in 2000, its resource management features had develop into leveraged for expend for stock of enterprise purposes. sizable organizations – chiefly ones formed through mergers and acquisitions – ended up with extra software than they knew what to Do with.

by the point the previous computing device acquaintances – now just CA applied sciences – received Niku and made it into its clarity division, application portfolio administration had spin into one in every of Niku’s top selling points. This morning, as clarity now officially enters edition 13, it’s being offered for the primary time as a provider. but even with a cloud-primarily based choice, readability should no longer be credit of chiefly as a cloud migration device for traffic components, however rather as a utensil for first evaluating even if the sort of migration is critical. This from CA’s personal vice chairman for advertising and marketing, in an interview with ReadWriteWeb.

“I suppose there’s been this whole, kinda, hype the residence everybody’s heard, ‘cloud, cloud, cloud, cloud, cloud.’ It’s in reality no longer low-priced to circulation every thing to the cloud,” remarks CA technologies vp Kelly Blice. “And it’s in reality now not necessary to circulation everything to the cloud, nor Do you exigency to.”

click for full-reveal.

In a advertising and marketing push this week for the novel clarity job Portfolio manager version 13, CA is touting the product’s absolutely redesigned entrance conclusion, which does look to borrow some ideas from Salesforce. the novel system is based mostly around a modularized dashboard that digests facts from distinct sources to provide a greater streamlined abstract. the sensation with extinct variations has been that, as initiatives develop into greater advanced and as clarity represents these projects, shall they embrace, faithfully, the responsibility for managing the information linked to those initiatives gets sloughed off onto the shoulders of the IT branch.

The purpose for v. 13 is to circulate the product returned to its original, circa 1984 goal audience: managers and traffic analysts.

click on for full-screen.

As a company in transformation, Blice remarks, “I should determine what I exigency to grasp to the cloud, what needs to be engaged on the cloud and what doesn’t, and what makes feel when. That’s in fact what readability means that you can do. In a transformational method, what we’ve accomplished is added performance, each with the aid of making the navigation very, very effortless for company users, for analysts, for managers making these choices along with americans who are actually the usage of the answer.”

The catchphrase CA’s UI designers stored in intellect, Blice tells us, as they were rebuilding readability’s front conclusion became, “Two Clicks to cost.” clarity clients may additionally Have a variety of roles inside their company – they may be challenge management officers (PMOs) organizing the portfolio (above), or personnel managers protecting their group of workers members to altering milestones (below). For yardstick initiatives in the application, they should noiseless most efficient grasp two clicks to reach what they need. And for functionality that may additionally definitely be buried deeper than two clicks, clients may noiseless be capable of personalize their dashboards in order that they are purchasable in a solitary or two clicks.

click for full-reveal.

within the first instance of gregarious integration for readability, the service now provides the choice to Have the search unavoidable planning solutions be crowdsourced among distinctive clients.

“What we’re hearing from their clients is that a lot of instances, they delivery with these concepts that they believe are what the consumers want, but someplace down the road they determine it’s now not. That can be [because] it’s now not the functionality that they need, it’s now not the provider they need. It may well be as a result of they can’t supply them the time they want, because they didn’t obtain it. So what we’ve completed to address that's, they Have the capacity to definitely crowdsource and supply ‘ideation’ to an organization. That enables them to maintain in understanding what their valued clientele need, and then with requirement planning, [assess] what their requirements are.”

in this context, the crowdsourcing conception lets assorted users, including the enterprise’s own purchasers, collaborate in defining mission goals. gregarious tools might be provided to let folks vote these concepts up or down. believe of Reddit for administration.

The incorporation of ideation lets a readability v. 13 user itemize consumer necessities, then test with various priorities for meeting these necessities in my conviction and over time, the usage of these vote casting tools. The utensil will assignment what supplies can be utilized for each trial run, and when those resources would develop into accessible for different initiatives again. “in case you prioritize them correct, another project isn’t going to forward along and grasp faultless your resources.”

readability PPM v. 13 remains made attainable now in its ordinary, on-premise structure, or alternately as a self-upgrading service through CA functions.

analysis and Markets: mission and Portfolio management (PPM) dealer landscape report: CA clarity PPM | killexams.com actual questions with brain dumps

DUBLIN--(company WIRE)--research and Markets (http://www.researchandmarkets.com/research/bce6d6/project_and_portfo) has introduced the addition of the "undertaking and Portfolio administration seller panorama file: CA clarity PPM" document to their providing.

This Branham group file is one in faultless a string of 9 reports that give an in-depth view of the venture and Portfolio administration (PPM) vendor panorama. This report in unavoidable covers CA technologies' PPM answer, CA clarity PPM. It evaluates CA clarity PPM throughout 44 technical standards, profiles the dealer and concludes with a detailed evaluation of the answer's universal strengths and weaknesses versus these of the other vendors that had been included as fraction of the evaluation (i.e. AtTask, Compuware Changepoint, Daptiv PPM, HP PPM middle, Microsoft EPM, Oracle Primavera, Planview commercial enterprise and Serena PPM). The report additionally provides a technical evaluation matrix that evaluates the capabilities of every of the 9 vendors' PPM solutions in keeping with a five metric scale (i.e. No support up to wide support).

Who should read: This document is essential useful resource for these searching for to evaluate pick PPM options and eventually create a short list of suitable candidates for extra analysis. The report also offers delivered standpoint for those corporations that are actively concerned within the PPM sector and exigency to stronger understand the competitors's technical capabilities and connected positioning.

Key issues coated:

company Overview

  • background
  • Key executive administration
  • economic Highlights
  • goal Market
  • companions
  • Product/service choices
  • primary clients
  • foremost rivals
  • Product Overview

  • solution accessories
  • support and features
  • characteristic performance

  • solution components
  • Core PPM facets and performance
  • person Interface
  • solution Resilience
  • Integration & Infrastructure
  • Branham assessment

  • essential Strengths and Weaknesses
  • summary
  • Appendix: PPM options - Technical evaluation Matrix 28

    groups outlined:

  • AtTask
  • CA technologies
  • Compuware
  • Daptiv
  • HP
  • Microsoft
  • Oracle
  • Planview
  • Serena
  • For greater information discuss with http://www.researchandmarkets.com/analysis/bce6d6/project_and_portfo

    INAIL taps CA readability PPM for budget control | killexams.com actual questions with brain dumps

    INAIL taps CA clarity PPM for funds handle - InsuranceNewsNet


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    Processing fixed and saved adipose-derived emanate cells for quantitative protein array assays

    Jessica S. Sadick1 and Eric M. Darling1,1, 2, three, four

    1Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown university, providence, RI2Center for Biomedical Engineering, Brown school, windfall, RI3School of Engineering, Brown school, providence, RI4Department of Orthopaedics, Brown college, providence, RI

    BioTechniques, Vol. sixty three, No. 6, December 2017, pp. 275–280

    Supplementary material


    accurately characterizing cellular subpopulations is elementary for elucidating the mechanisms underlying general and pathological biology. Isolation of selected mobile kinds will also be achieved through labeling enjoyable phone-linked proteins with fluorescent antibodies. cell fixation is common to prepare these samples and allow for lengthy-term storage, however this poses challenges for subsequent protein evaluation. They previously established the FITSAR (formaldehyde-fastened intracellular goal-sorted antigen retrieval) formula, in which protein can also be isolated and characterized from fastened, enriched mobilephone subpopulations. prerogative here, they enrich on this formula by using allowing compatibility with incredibly sensitive multiplex protein arrays and demonstrating applicability to long-time term kept samples. Feasibility experiments established parallel detection of cell adhesion molecules (CAMs) the expend of an enzyme-linked immunosorbent assay (ELISA) panel with human adipose-derived emanate cells (ASCs) saved for as much as 1 month.

    telephone type-specific protein characterization is elementary for accurate figuring out of ordinary and pathological biology. The ability to extract protein from mounted cells raises flexibility in sample preparation and the expertise for intracellular target-primarily based enrichment. They previously centered the FITSAR (formaldehyde-fastened intracellular target-sorted antigen retrieval) method, during which protein is remoted and characterised from fastened enriched cellphone populations (1). the usage of adipose-derived emanate cells (ASCs) as their mobilephone class of pastime, they extend and improve upon FITSAR with two aims: (i) to validate protein isolation from mounted and saved single-telephone suspensions and (ii) to panoply detection of remoted proteins via enzyme-linked immunosorbent assay (ELISA) arrays.

    formulation abstract

    here, they existing a technique through which protein from stored formaldehyde-mounted samples may be assessed on high-throughput, multiplex, enzyme-linked immunosorbent assay (ELISA) arrays.

    A multi-donor human ASC superlot (passage 5) (#36; Zen-Bio Inc., analysis Triangle Park, NC) become used for faultless experiments. ASCs were cultured in medium containing DMEM/F12 (Cat. #SH30023.01; HyClone, Logan, UT), 1% antibiotic/antimycotic (Cat. #SV30079.01; HyClone), 10% fetal bovine serum (FBS) (Cat. #SER-500; Zen-Bio Inc.), 1 ng/mL fibroblast enlarge factor (FGF) (Cat. #233-FB), 5 ng/mL epidermal boom factor (EGF) (Cat. #236-EG), and nil.25 ng/mL transforming growth ingredient-β1 (TGF-β1) (Cat. #240-B) (all enlarge elements from R&D methods, Minneapolis, MN) (2) and had been maintained at 37°C, 5% CO2.

    To be confident reproducible protein isolation from cells chemically fastened in four% paraformaldehyde (PFA) (Cat. #28906; ThermoFisher Scientific, Waltham, MA) as in comparison with fresh samples, protein extraction protocols had been assessed by pass of complete protein quantity (Pierce BCA Assay package, Cat. #23225; ThermoFisher Scientific) and excellent on a Coomassie Blue (MP Biomedicals LLC, Santa Ana, CA)–stained web page gel (precast gel, Cat. #456-9033; Bio-Rad, Hercules, CA) (n = 3). sparkling and PFA-mounted ASCs Have been lysed both on ice or via boiling (n = 3). Lysis buffer changed into composed of Tris-HCl and SDS, as well as protease/phosphatase inhibitors (Halt Protease and Phosphatase Single-Use Inhibitor Cocktail, one hundred×; Cat. #78442, ThermoFisher Scientific) (particulars in desk 1 and the Supplementary Protocol) (three). No massive change in protein yield or banding became observed between the gold yardstick manner using sparkling ASCs lysed on ice (Fr-i) (4) and the mounted/boiled manner (PFA-b) (P > 0.05) (figure 1A, Supplementary figure S1). additionally, findings were equivalent when the expend of formalin (four% PFA + 1.5% methanol) or simple four% PFA fixatives (Supplementary determine S2). As corroborated by using the literature involving formalin-mounted paraffin-embedded (FFPE) samples, a success protein extraction from fastened samples requires exposure to formaldehyde scavenging and denaturing reagents (high concentrations of both Tris-HCl and SDS) apart from unreasonable heat to advertise protein untangling and methylene bridge thermal hydrolysis (three,5,6).

    desk 1. 

    Being able to evaluate kept, fixed samples would enhance the consumer flexibility of the FITSAR process. PFA-fastened ASCs were suspended in PBS and saved at four°C for 0–28 days. After storage, samples had been lysed with the aid of boiling and assessed for total extracted protein yield and fine (n = 3). mounted cells may well be stored for as much as 7 days before present process a minor however statistically huge reduce in total protein yield (P < 0.02) (determine 1B). The ~15%–20% reduce between days 0–14 and 0–28 didn't bear visible adjustments in protein banding profiles among samples isolated throughout faultless storage situations (determine 1B). This recommended that the collected protein is generally representative of the sample’s proteome and that any loss is homogeneously allotted throughout protein types.

    ELISA arrays, a platform through which diverse proteins of hobby (POIs) can be detected concurrently at picomolar concentrations, had been chosen to prove the accelerated compatibility of FITSAR with different protein analysis ideas. ELISA arrays are incompatible with the SDS within the customary FITSAR sample processing steps, since detergents obtrude with antigen–antibody interactions through forming adducts with protein residues (7). therefore, the FITSAR pattern processing system was adjusted to consist of an SDS-exclusion step the expend of commercially available, detergent-casting off resin spin columns (Pierce Detergent elimination Spin Columns, Cat. #87776/#87777; ThermoFisher Scientific). a success SDS removal from mounted cellphone lysates was established using the Stains-all Assay (Cat. #213512500; Acros Organics, Geel, Belgium) (8,9), and protein yield turned into quantified. more than ninety nine.99% of the SDS became removed, as evidenced via the lack of a credit SDS absorbance height at 440–450 nm wavelength for faultless processed samples (determine 2A). Protein loss within the columns dissimilar reckoning on column measurement. For wee columns (10–25 L sample volume), the yield of eluted protein changed into not greatly different from the volume of loaded protein (P = 0.29) (n = three) (Supplementary figure S3A). For gargantuan columns (25–a hundred L sample quantity), the yield of eluted protein turned into significantly below the volume of loaded protein (P < 0.001) (n = 3) (Supplementary determine S3B). despite measurement, these spin columns characteristic by pass of offering a hydrophobic microenvironment within the resin cavity into which wee nonpolar compounds, akin to SDS, infiltrate and due to this fact kind an inclusion complicated (7). Non-selected adsorption or entrapment of protein is expected to be dispensed evenly across protein kinds, resulting in a detergent-free protein lysate it really is representative of the customary pattern proteome.

    As a proof-of-conception, SDS-purified ASC storage protein lysates (n = three) were assessed using a multiplex human telephone adhesion molecule (CAM) ELISA array (QAH-CAM-1; RayBiotech, Norcross, GA). Isolation of cell-surface/membrane-certain proteins from fastened samples is notoriously variable compared with proteins remoted from the cytosol or nucleus (10,11), thus presenting a difficult examine of the reliability and rigorousness of the processing worried in the up-to-date FITSAR method. every CAM ELISA array consisted of 17 POIs (desk 2) printed in technical quadruplets. A six-factor typical curve become used for quantification. Of the 17 CAM POI available, eight were doubtlessly expressed in the ASCs, given their species, origin, and passage quantity (12-14). of those 8 POIs, 6 Have been detected, with 5 of the 6 proteins having no significant change in expression level amongst sparkling, fastened, and fixed/kept samples (P > 0.05) (figure 2B). most efficient ICAM1 expression modified enormously, being larger in Day 7 and Day 28 fixed samples in comparison with Day 0 sparkling and stuck samples (P < 0.02). This discrepancy is most likely because of the variety associated with these types of microarrays (15). however, yet another probability is unforeseen jaundice favoring ICAM1 isolation faultless the pass through processing (i.e., ICAM1 extraction became more efficient than extraction of alternative proteins, leading to an artificially inflated value after normalization to total protein degrees). For faultless different proteins assessed, no modifications from the gold typical manner changed into observed.

    desk 2. 

    Our greater manner allows the assessment of stored fastened samples and the expend of low-protein, high-throughput ELISA arrays. The improvements to pattern processing, in particular detergent elimination, additionally provide talents compatibility with suggestions akin to mass spectrometry. with the aid of pairing these improvements with their FITSAR formula, mobilephone subpopulations of interest will also be isolated and their protein expression profiles analyzed with flexibility in timing and the expend of delicate, quantitative assays. writer contributions

    J.S.S. and E.M.D. designed the examine and wrote the manuscript. J.S.S. performed faultless of the experimental work. Acknowledgments

    This drudgery changed into supported by pass of the countrywide Institutes of health (R01AR06304 to E.M.D.) and country wide Science groundwork (profession CBET 1253189 and eager CBET 1547819 to E.M.D., GRFP 2014183678 to J.S.S.). This paper is domain to the NIH Public entry policy.

    Competing hobbies

    The authors declare no competing interests.

    CorrespondenceAddress correspondence to Eric M. Darling, a hundred seventy five meeting street, Brown school, windfall, RI 02912. e mail: [email protected]References1.) Sadick, J.S., M.E. Boutin, D. Hoffman-Kim, and E.M. Darling. 2016. Protein characterization of intracellular goal-sorted, formalin-fastened cell subpopulations. Sci. Rep. 6:33999. 2.) Estes, B.T., B.O. Diekman, and F. Guilak. 2008. Monolayer mobile enlargement conditions impress the chondrogenic capabilities of adipose-derived emanate cells. Biotechnol. Bioeng. 99:986-995. 3.) Kawashima, Y., Y. Kodera, A. Singh, M. Matsumoto, and H. Matsumoto. 2014. efficient extraction of proteins from formalin-fastened paraffin-embedded tissues requires greater awareness of tris(hydroxymethyl)aminomethane. Clin. Proteomics eleven:4. 4.) Mahmood, T., and P.C. Yang. 2012. Western blot: approach, conception, and barrier shooting. N. Am. J. Med. Sci. four:429-434. 5.) Magdeldin, S., and T. Yamamoto. 2012. towards deciphering proteomes of formalin-fastened paraffin-embedded (FFPE) tissues. Proteomics 12:1045-1058. 6.) Addis, M.F., A. Tanca, D. Pagnozzi, S. Crobu, G. Fanciulli, P. Cossu-Rocca, and S. Uzzau. 2009. generation of exceptional protein extracts from formalin-mounted, paraffin-embedded tissues. Proteomics 9:3815-3823. 7.) Antharavally, B.S., okay.A. Mallia, M.M. Rosenblatt, A.M. Salunkhe, J.C. Rogers, P. Haney, and N. Haghdoost. 2011. efficient elimination of detergents from proteins and peptides in a spin column structure. Anal. Biochem. 416:39-44. eight.) Rupprecht, ok.R., E.Z. Lang, S.D. Gregory, J.M. Bergsma, T.D. Rae, and J.R. Fishpaugh. 2015. A precise spectrophotometric formula for measuring sodium dodecyl sulfate awareness. Anal. Biochem. 486:seventy eight-eighty. 9.) Rusconi, F., E. Valton, R. Nguyen, and E. Dufourc. 2001. Quantification of sodium dodecyl sulfate in microliter-quantity biochemical samples by using seen effortless spectroscopy. Anal. Biochem. 295:31-37. 10.) Nirmalan, N.J., P. Harnden, P.J. Selby, and R.E. Banks. 2009. structure and validation of a novel protein extraction methodology for quantitation of protein expression in formalin-fastened paraffin-embedded tissues the usage of western blotting. J. Pathol. 217:497-506. eleven.) Crockett, D.okay., Z. Lin, C.P. Vaughn, M.S. Lim, and ok.J.S. Elenitoba-Johnson. 2005. Identification of proteins from formalin-fastened paraffin-embedded cells by means of LC-MS/MS. Lab. invest. eighty five:1405-1415. 12.) Zuk, P.A., M. Zhu, P. Ashjian, D. De Ugarte, J. Huang, H. Mizuno, Z. Alfonso, J. Fraser. 2002. Human adipose tissue is a source of multipotent emanate cells. Mol. Biol. mobilephone 13:4279-4295. 13.) Katz, A.J., A. Tholpady, S.S. Tholpady, H. Shang, and R.C. Ogle. 2005. phone floor and transcriptional characterization of human adipose-derived adherent stromal (hADAS). emanate Cells 23:412-423. 14.) Mitchell, J.B., okay. McIntosh, S. Zvonic, S. Garrett, Z.E. Floyd, A. Kloster, Y.D. Halvorsen, R.W. Storms. 2006. Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and emanate telephone–linked markers. emanate Cells 24:376-385. 15.) Berg, D., S. Hipp, okay. Malinowsky, C. Böllner, and okay.F. Becker. 2010. Molecular profiling of signalling pathways in formalin-mounted and paraffin-embedded cancer tissues. Eur. J. cancer forty six:forty seven-fifty five.

    Cambridge Pixel Unveils HPx-346 Analogue to community Radar Video records Converter | killexams.com actual questions with brain dumps

    CAMBRIDGE, England, July 25, 2017 /PRNewswire/ --

    - HPx-346 is a wee profile aspect basic radar enter and community radar video distribution card that converts analogue radar into a typical ASTERIX CAT-240 network statistics circulate 

    - HPx-346 gives a price-advantageous means of importing radar facts into a latest reveal; as an example, the cardboard would enable current radars on a ship or traffic boat to be obtainable in an ECDIS gadget 

    - Cambridge Pixel will be showcasing its HPx-346 card and other products on stand S4-352 (South corridor) on the DSEI Defence and protection exhibit in London from 12-15 September 2017. 

    Cambridge Pixel, a traffic enterprise of radar monitor, monitoring and recording sub-systems, has introduced the HPx-346, a compact, low energy (lower than 5 Watts), standalone fundamental radar input and network distribution card.

    The HPx-346 is designed to transmute analogue radar signals into a typical open community data movement such as ASTERIX CAT-240. the card offers a cost-useful pass of importing analogue radar records into a latest screen.

    The wee profile aspect (149x74mm) HPx-346 card aspects a mixed ARM/FPGA device-on-chip processor to deal with the radar acquisition and data conversion. the card may well be configured through a web interface with settings made to the cardboard for self sustaining operation. however, a programming API is obtainable to permit far flung manage and set-up.

    David Johnson, CEO, Cambridge Pixel, referred to: "we've viewed a pair of applications that require a compact, low energy, standalone unit able to converting radar alerts into community information. as an example, the HPx-346 would enable present radars on a ship or industrial boat to be obtainable in an ECDIS (electronic Chart screen and guidance device) screen.

    The HPx-346 complements their present ambit of HPx PCI and PCI express radar enter cards and provides system integrators a choice between the wee dimension and low power of the HPx-346 and a plenary computer-primarily based radar server incorporating their HPx-200 or HPx-400e sequence playing cards."

    The HPx-346 supports a wide variety of signal varieties and enter voltages together with differential and single-ended indicators with selectable mark tiers and enter impedances. This allows connection to a various ambit of traffic and armed forces radar kinds together with those from Furuno, JRC, Kelvin Hughes, Koden, Raytheon, Sperry and Terma. The HPx-346 accepts radar video, set off and azimuth signals within the type of ACP/ARP.

    The HPx-346 can also be configured as a standalone radar processor with the cardboard installed within present device, or provided in a compact enclosure. A progress package is obtainable comprising the card, vigor supply, RadarView utility and a utility progress library.

    Cambridge Pixel's HPx-346 is fraction of a household of radar acquisition and processing add-ons that deliver gadget integrators with a powerful toolkit to construct server and customer panoply systems. The business's world-main SPx suite of utility libraries and functions deliver enormously flexible, equipped-to-run utility items or 'modules-of-expertise' for radar visualisation, radar video distribution, plot extraction and goal tracking.

    Cambridge Pixel's radar know-how is utilized in naval, air site visitors manage, vessel traffic, traffic shipping, security, surveillance and airborne radar applications. Its systems had been applied in mission Important applications with corporations such as BAE programs, Frontier electronic systems, Lockheed Martin, Barco Defence, Blighter Surveillance systems, Exelis, Kelvin Hughes, Navtech Radar, Raytheon, Royal Thai Air drive, Saab, Hanwha, Sofresud and Tellumat.

    Cambridge Pixel might be showcasing its HPx-346 card and different items on stand S4-352 (South hall) at the DSEI Defence and security demonstrate in London from 12-15 September 2017.

    For extra guidance in regards to the HPx-346 card and other items from Cambridge Pixel, gratify search recommendation from http://www.cambridgepixel.com or call: +forty four(0)1763-852749 or electronic mail: enquiries@cambridgepixel.com.

    Media picture:  


    statistics sheet: 


    About Cambridge Pixel (http://www.cambridgepixel.com)

    headquartered in 2007, Cambridge Pixel is an award-successful developer of sensor processing and panoply solutions together with primary and secondary radar interfacing, processing and expose components for military and industrial radar functions. it's an international-leading company of application-based mostly radar tracking and scan conversion options through its modular SPx application, and HPx hardware product latitude. based mostly immediate Cambridge within the UK, the traffic operates international through a network of agents and distributors.

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